Regenerative Aesthetics™ (PRP Training, Microneedling, Exosomes) Accredited Certification
Since 2014, PracticalCME has delivered the first accredited training in the cosmetic uses of PRP (Platelet-Rich Plasma) and later expanded to include microneedling and exosome applications. In 2025, this comprehensive curriculum was rebranded as Regenerative Aesthetics—a modern, evidence-based program that unifies PRP, microneedling, and emerging biologics into one certification pathway.
Complete 7 hours of self-paced online learning featuring 50+ primary-literature references, then add optional MD-taught hands-on training in a small-group setting in 12 locations nationwide. If you’ve been searching for PRP training or microneedling training, this is the evolved, accredited course that covers both—now under the Regenerative Aesthetics banner.
Start Your Career-Changing Regenerative Aesthetics™ Certification in 3 Easy Steps
Since 2012, PracticalCME is the PREMIUM, Small-Group, Hands-On Class for Cosmetic PRP, Microneedling and Exosome Training that teaches you how to incorporate these revolutionary non-drug services into your aesthetic practice.
- Fully CME-Accredited Certification backed by 12 AMA PRA Category 1 Credits™ from AAFP and accepted by ANCC, AANP, AAPA.
- Add On Botox and Filler Hands-On
- Learn Online before Hands-On. This is the FAST TRACK® Blended Online followed by Live Hands-On that we pioneered in 2012. Watch at your leisure and complete before the live date. Arrive at hands-on Prepared… not Scared. Register today and begin learning tonight.
- 0% Financing Available. Apply in checkout through our partner Affirm.
- 2025 TOP PICK for PRP Training at aesthetic-training.com
- LIVE CHAT with us right now (bottom right of screen) if you have questions.
1️⃣ Choose Your Live Date in one of 12 Hands-On Locations
Scroll Down for the Latest Live Dates.
Or Select Your City using the LIVE TRAINING DATES menu item.
2️⃣ Complete the Accredited Online Regenerative Aesthetics™ Training Module
Customizable consent forms, patient instructions, and narrated case videos are also included.
Then, print your first CME certification.
You keep the online access and receive free unlimited updates for 2 years.
3️⃣ Attend the Live Hands-On
At our small-group, MD-taught hands-on, join us for PRP and Microneedling hands-on with your MD instructor in a group averaging 4 students per date. At that time, you will then receive your second certification for “hands-on” PRP and Microneedling. All sites offer hands-on multi-depth Medical Microneedling. Clinical office sites spin PRP for use and a topical and for injection. See the Course Description for the city you are interested in for more information.
Now you are fully hands-on certified to start ordering products and begin your practice in accordance with state supervisory rules and regulations.
We are here for your success, before, during and after your training.
📍🗓️🛒REGISTER NOW: Live Dates and Locations
Bundle PRP and Microneedling Training with Botox and Filler on the same day for more savings and up to 23 CME Credits!
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4-PROCEDURE (Botox, Filler, PRP, Microneedling & Exosomes) FAST TRACK® Hands-On Certification Saturday August 23, 2025 8am, New York (Babylon, Long Island) (23 credits) 🟢2+ SEATS LEFT🟢
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Regenerative Aesthetics™ (Microneedling, Exosomes, PRP Training) FAST TRACK® Hands-On Certification Saturday August 23, 2025 1:00pm New York (Babylon, Long Island) (12 credits)🔴SOLD OUT🔴
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4-PROCEDURE (Botox, Filler, PRP, Microneedling & Exosomes) FAST TRACK® Hands-On Certification Saturday August 23, 2025 8am, West Palm Beach (23 credits) 🟢2+ SEATS LEFT🟢
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Regenerative Aesthetics™ (Microneedling, Exosomes, PRP Training) FAST TRACK® Hands-On Certification Saturday August 23, 2025 1pm West Palm Beach (12 credits) 🟢2+ SEATS LEFT🟢
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📃Regenerative Aesthetics™ Course Outline
🖥️ All Courses Feature Blended Online + Live FAST TRACK Training
🖋️ Hands-On Microneedling Treatment under direct MD Supervision
🩸PRP isolation and hands-on injection of PRP under supervision.
(Atlanta, Phoenix, Chicago, Seattle, San Francisco, Anaheim, and San Diego are hotel-based courses injection hands-on without spun PRP, but at a discounted tuition)
👨⚕️One-On-One MD Supervised Hands-On (Limit 5 per Class)
🎗️12 CME Credits with 2 Years’ Online Access and Free Updates
Day 1: PRP and Microneedling Training Course (Online at Your Own Pace)
Course Includes over 50 clickable citations from the Medical Literature
Isolating Platelet-Rich Plasma (PRP)
- Understand the Definition of Platelet-Rich Plasma (PRP) facial procedure
- Learn the growth factors present in platelets and their functions
- Review the FDA-approved PRP isolation devices
- Strengths and Weaknesses of Each
- Differences between 1.7x and 4x or higher platelet counts
- How and Why to “Activate” PRP
- Why PRF is worse than PRP and should be avoided.
- Benefits of PRP in the medical literature
- Medical/Wound Healing Indications
- Review of Literature regarding cosmetic indications
- Face lifting and filling
- Skin tone and uniformity
- Hair Regrowth
- Scars
- Pigment, Acne and other indications
Performing the PRP Facelift (Vampire Facelift Training)
- Cosmetic PRP Facelift Technique and Protocols
- Patient Assessment
- Planning the Treatment
- Volumes of PRP and HA Filler Calculations
- Performing the Procedure
- Aftercare
- Using PRP for other Body Areas
- Scalp Rejuvenation Protocols
- Hand Rejuvenation Protocols
- Cosmetic PRP Breast Atrophy/Nipple Protocols
- PRP Scar revision Protocols
Microneedling Training with and without PRP
- Principles of Microneedling
- Skin Layers, target cells and Microneedling literature review
- Review of Microneedling Devices
- FDA 2018 Jurisdiction of Microneedling Devices
- Microneedling RF is NOT Microneedling
- Microneedling protocols
- Scars
- Scalp
- General Anti-Aging
- VItiligo
- Stretch Marks
- Pigment and sun damage
- Needling Depth vs Skin Endpoints
- Aftercare and Skin Products to Avoid
Exosomes
- Definition
- Origins
- Contents
- FDA Jurisdiction
- Literature Review of Exosomes
- Split-Face Studies
- Using Exosomes with Microneedling
- Exosomes vs PRP
- Red LED Light Therapy Indications and Literature Evidence
Using PRP with Microneedling (Vampire Facial)
- Indications
- Depth Protocols
- Technique
- Is Activation Necessary?
- Repeat Treatments
- Home Care Instructions
- BONUS: Introduction to PRP with Smooth PDO Threads
- Marketing Your New Service
- Bundling Your Service With BTX and Dermal Fillers
Day 2: LIVE Hands-On PRP and Microneedling Training Hands-On Certification (Date and Location on Your Reservation)
Advanced review of PRP Protocols and Patient Selection
Advanced review of Microneedling Protocols and Patient Selection
Q&A with Advanced tips and tricks.
LIVE Office-Based Training courses will include hands-on PRP Injection and Microneedling. LIVE Hotel-Based (Atlanta, Phoenix, Seattle, Chicago, San Diego, San Francisco, Anaheim) Training courses will include hands-on Microneedling.
🏅CME Accreditation Statement
- PRP CME and Microneedling CME on the Same Date. Blended Online + Live PRP CME Certification
- Accredited Certification
- Credits accepted by AANP , AAPA, and ANCC
- THIS ACTIVITY HAS BEEN REVIEWED AND IS ACCEPTABLE FOR UP TO 12 ELECTIVE CREDITS BY THE AMERICAN ACADEMY OF FAMILY PHYSICIANS (AAFP).
- AAFP Elective credit is accepted by the American Medical Association as equivalent to AMA PRA Category 1 Credit™ toward the AMA Physician’s Recognition Award.
⏩ About Blended FAST TRACK® Online + Live Training
First, Reserve your spot in one of our blended FAST TRACK Training Courses for the Date and Location of your Choice.
Then Watch the Online training at your own pace. Follow clickable links and interact with our faculty for any questions you have. When finished, complete the online post-test.
DOWNLOAD/PRINT CME CERTIFICATE #1
Finally, Attend the Live Hands-On Date and Complete Your Small-Group Hands-On Training in Botox and Dermal Fillers.
RECEIVE HANDS-ON CME CERTIFICATE #2
🖥️Course Video and Eligibility
Regenerative Aesthetics Training Course Video
Microneedling and PRP Training for Medical Professionals is open to …
- Doctors (MD’s and DO’s)
- Nurse Practitioners & Physician’s Assistants
- Registered Nurses (RN’s)
- ND’s in Washington, California and Arizona.
- Non-US Licensed Providers and other licensure (like aestheticians) can only take the online course, but not hands-on in the USA
⭐⭐⭐⭐⭐ Course Reviews
Dr. Zengo
I am so thankful I found your company for my education. After taking your courses, my fear of not mastering these skills faded into excitement and confidence.
As I move forward, I will have questions. Knowing that you are willing to be a resource and answer those questions adds an additional layer of confidence that I can safely reach my goals.
Your passion and dedication to excellence is a gift you share with your students. Thank you so very much.
Read MoreP.W.Botox Filler Atlanta July 2025Fantastic! I completed PracticalCME training for BTX-A, Fillers, and Microneedling. From the beginning, I could not have asked for better! Dr. Zengo is extremely responsive to questions, phone calls, emails, online chats. He is so knowledgeable. The online didactic was clear and concise. There was so much covered in the lecture. I appreciated the downloadable and printable slides for note taking and reference. For the hands on training, I spent the day with Dr. Roop Monica Gill. The day was full of useful knowledge. She is a rock star! She is knowledgeable, highly skilled, approachable, and extremely personable. I feel like I have a new colleague and friend! Some of the additional information I obtained from this class was regarding legality and business tips. This information is crucial. I would highly recommend this course to anyone interested in pursuing medical aesthetics.
Read MoreSuzanne Venuti-CohenWest Palm Beach July 2025Great class! Any time you leave with more than expected it is a good feeling. The PracticalCME PRP Training class was just that from start to finish. Dr.Huyen Transform Aesthetic Center was the perfect ending. Her center was a relaxing and comfortable place to learn a new skill. She and her staff made you feel welcome. Gave informative real-life applications. Made sure we had a firm understanding of the information and could perform all steps of the procedure.
Read MoreKathleen ChristianKChristian LCC Orlando PRP Training July 2022Online didactic material was comprehensive and thoroughly addressed all aspects of treatment. Dr. Huyen provided exceptional hands on training in a professional and supportive setting. I highly recommend this course and live training.
Read MoreMolly SimpsonOrlando April 2022I really learned a lot in a matter of 6 hours. It was truly hands on and the small group size was perfect for that. Dr. Huyen was very knowledgeable and personable. I was a novice when I arrived and left feeling comfortable doing all three procedures. I highly recommend the course.
Read MoreMihaela CarterOrlando BTX/Filler/PRP April 2022Excellent course
Read MoreNidal RadwanPracticalCME Hands-On TrainingThis course and the hands on instruction will truly be a game changer for my new practice.
Read MoreTammy CarterHands-On Course 2021Great experience! Highly recommended.
Read MoreKarlaNovember 2020 PRP BTX/FillerAwesome course
Read MoreGreat hands on experience. Highly recommend.
Read MoreLynsey MaterniOrlando PRP November 2020Dr. Zengo is a fabulous teacher. Great hands on. Very thorough. I feel like I have a great foundation and I’m ready to start practicing. Am going to take more courses with this group. Thank you for a great informative experience.
Read MoreKacian Brown, MDOrlando BTX/Filler PRP November 2020The online learning was outstanding. And then the hands-on class surpassed my expectations. Excellent instruction aimed at getting the most hands-on experiences for each student with Botox, Fillers, & PRP. The small class was just perfect. So glad I chose Practical CME....I will definitely use them again!
Read MoreThis is a great way to get hands on training on using facial fillers, Botox and PRP. I learned about marketing , safety, patient selection and accurate patient evaluation. Overall, it's an enjoyable day packed with information. The instructors are very experienced but still remember how it feels to learn a new skill. They are patient and fun.
Read MoreVery thorough. Hands on portion was informative and we left the day feeling ready to start practicing the new skills we learned.
Read MoreGreat class, very informative.
Read MoreJulie Root, RNPRP LA 10/19Very informative, hands on was perfect! Will definitely be signing up for other classes.
Read MoreKaren O’DayLA 10/19 EverCare Family Practice LLCYour class is very structured and informative. Thank you very much .
Read MoreEden DabalusBTX/Fillers PRP Los Angeles October 2019Thank you, Dr. Zengo, for your amazing evidence based streamline courses in Botox, dermal fillers, PRP, and microneedling followed by a wonderful day of clinical application. The relaxing atmosphere, small intimate group with individual IPADS highlighting the important talking points was a nice touch. Your expertise was apparent in your clinical demonstration and your patience inspired confidence in your participants. A special thanks for introducing material tailored for my years of experience. We can all learn from you. You're a great teacher! I look forward to other courses.
Read MoreI am 100% confident I can implement this in my practice.
Well presented by someone who is definitely an expert in the field.
Read More
Frequently Asked Questions about Regenerative Aesthetics™ PRP, and Microneedling Training
What is Regenerative Aesthetics™ training?
Regenerative Aesthetics™ is our newly rebranded, accredited training program that unites Cosmetic PRP (Platelet-Rich Plasma), microneedling, and exosome therapy plus other non-invasive, evidence-based technologies like red LED light, into one evidence-based course. Formerly known as PracticalCME’s PRP Training Certification, it now offers a broader scope while retaining the same trusted CME-accredited standards we’ve upheld since 2014. Everything in the course is non-drug and does not require expensive equipment to perform.
Does the Regenerative Aesthetics™ course include PRP training?
Yes. Our Regenerative Aesthetics™ program fully covers cosmetic PRP applications, spinning, and isolating the product in an FDA-compliant manner and activating it for maximum benefit, making it ideal for providers searching for accredited PRP training. The curriculum includes over 50 primary-literature references, updated protocols, and optional small-group hands-on training with experienced MD instructors.
Is microneedling certification included in the Regenerative Aesthetics™ course?
Absolutely. Microneedling training is an integral part of the Regenerative Aesthetics™ program. You will learn advanced techniques, device selection, depth and combination protocols with PRP, exosomes and home care, culminating in a certification recognized for CME credit. for doctors, nurses and PA’s.
How does this course compare to other PRP or microneedling training programs?
PracticalCME’s Regenerative Aesthetics™ course is unique in offering a blended learning format—self-paced online modules plus optional MD-taught, small-group hands-on. Unlike many short, lecture-only PRP training or microneedling certification classes, we emphasize evidence-based practice, safety, and personalized instruction.
Who can enroll in Regenerative Aesthetics™ , PRP, and microneedling training?
The course is open to qualified medical professionals including MD, DO, NP, PA, RN, and in some states, DDS and NMD. Whether you are searching for PRP training, microneedling training, or both, this single program delivers comprehensive, accredited instruction for all scopes of practice.
Cosmetic Platelet-Rich Plasma Hands-On Certification with Microneedling Training
Since 2008, PracticalCME has been a leader in small-group, hands-on PRP Training. Moreover, our Cosmetic PRP Course is also combined with a complete Microneedling Curriculum as well. Therefore, you will learn two of the most sought after injectable cosmetic treatments in one certification course. This effectively covers both the PRP Facelift and PRP Facial in one Training.
As a result, over 98% of our attendees rate our PRP Training Course “excellent” and would recommend PracticalCME’s certification to a friend or colleague.
FAST TRACK™ Online plus Live Hands-On Blended Dual Certification
- A full 7-hour streaming, interactive online presentation complete with narrated treatment videos.
- Because the online learning begins from the moment you place your order, you can learn at your own pace.
- Then, print your online CME certificate after passing the online post-test.
- Then, attend the live hands-on for an additional 5 CME hour certificate.
- Hands-on courses are limited to 4-6 providers for each 1 MD instructor
One-on-One Small Group PRP and Microneedling Hands-On Training.
Because our MD instructors average 10 years of experience, your semi-private hands-on experience is second to none. You get to perform your own medical microneedling at all sites and inject real PRP spun from one of your own patients at our private MD office sites (West Palm Beach, Washington DC, Orlando/Daytona Beach, Los Angeles (Irvine, CA), New York, Charlotte). In addition, we only use FDA-cleared microneedling pens and PRP isolation devices, and have NO sponsors controlling our curriculum like other trainings.
Why Choose PracticalCME for your PRP Facelift Certification and Microneedling Training?
- Experienced: First, we have been in business since 2008 and have only MD instructors with at least 10 years’ experience.
- Dependable: Also, PracticalCME has never cancelled a class.
- Comprehensive: Spend as much time as you need on the online materials. Receive free updates and re-review as often as needed for 2 full years after purchase.
- Prepared: Because everyone learns the online material in advance, you already know the basics when you attend the live date.
- Personalized: Since no hands-on class has more than 6 participants, you will get the most personalized, one-on-one instruction.
- Helpful: Finally, customizable consents and patient instruction forms can be downloaded from the online course for use in your own practice.
In conclusion, no training course alters the legal scope of practice as defined by the medical/nursing boards in your home state/country. Therefore, please review all state/country requirements for supervision for these procedures prior to adding them to your practice
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