PRP Training Los Angeles with Microneedling Hands-On Certification in Orange County, CA
Why Take Regenerative Aesthetics (PRP, Microneedling, Exosomes) Training in Los Angeles from PracticalCME?
Since 2008, PracticalCME has taught PREMIUM, Small-Group, 12.75 Hour Blended Online plus Hands-On Classes for Regenerative Aesthetics in the Los Angeles (Orange County, CA) Area, and is the ONLY PRP Training Provider in Los Angeles that does ALL of the following…
- We have an All-MD Faculty. You know the Board-Certified MD who is teaching you, and the exact location of the course in Orange County before registration. PracticalCME is the only provider that gives this full transparency.
- We Only Teach in Small Groups. Our Live hands-on typically has 3-4 per class.
- CME-Accredited Certification by AMA, AANP, and ANCC for Doctors, PA’s, Nurse Practitioners, and Nurses
- Botulinum Toxin and Filler Certification on the same day. Nobody else gives you this flexibility.
- Location Transparency. You know the street address of the class BEFORE you register.
- We Deliver the Entire Course Online at Time of Registration. This is the FAST TRACK™ Blended Online followed by Live Hands-On that we pioneered in 2012. You can register today and begin learning tonight.
- No Sponsors, Ever! No vendors, exhibitors, proprietary products, memberships, or multi-level training scams. Just complete, unbiased, evidence-based training.
- 🏆2026 TOP PICK status awarded by aesthetic-training.com for their highest rated training programs.
- 0% Financing Available with our partner Affirm.
Thanks for reading. Please chat or email our medical director right now, just click LIVE CHAT link at the bottom of the page. Ask us anything!
❔What is the PracticalCME Difference?
Attend the PRP Certification Training in Southern California and Practice Confidently!

You are only taught by MD’s who have built successful full-time aesthetic practices. Learn from a MD’s who have hired and supervised aesthetic RN’s and NP’s, not traveling social media personalities with little experience building a successful real-world practice.
Importantly, PracticalCME teaches no “Advanced” level courses. You learn everything that works and is demand from our one comprehensive PRP/Microneedling course. No need to waste money on “advanced” or “Level 2” courses.
In addition, NP’s cannot be trained by RN’s and MD’s cannot be trained by NP’s or RN’s in an accredited CME environment. We have had to re-train hundreds of students who wasted their time with unaccredited training in the past.
With PracticalCME, you get Premium, Small-Group PRP Training in Los Angeles that fully certifies you to have the skills to excel, and support for 2-Years at no extra charge. All of this for about the same price as the unaccredited, non-transparent, large group, nurse-taught training programs.
See how PracticalCME compares side-by-side to other training programs.
🥼Meet Your Two MD Faculty for Los Angeles Certification Courses
Your instructor in Los Angeles
He has built a successful ⭐⭐⭐⭐⭐ practice from scratch and incorporates the best of all aesthetic modalities and under one roof. He has extensive experience training RN’s and NP’s who have gone on to full, successful aesthetic careers in his own practice and throughout the country.
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The instructor for your Online portion and Anaheim, CA hands-on is
Once you register, you will be encouraged to contact either of your physician faculty members with any questions you might have before, during and after your training is complete.
🏅CME Accreditation Information
- Regenerative Aesthetics PRP, Microneedling) CME
- 12 CME credit Hours (7 online and 5 live hands-on session hours)
The AAFP has reviewed Platelet-Rich Plasma (PRP), Microneedling and Exosomes in Cosmetic Medicine, and deemed it acceptable for AAFP credit. Term of approval is from 03/15/2025 to 03/14/2026. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- If this course is taken along with the morning BTX/Filler course, 23 CME Credits are earned.
⏩ About Fast Track® Online + Live Training from PracticalCME
First, Reserve your spot in one of our blended FAST TRACK Training Courses for the Date and Location of your Choice.

Then Watch the Online training at your own pace. Follow clickable links and interact with our faculty for any questions you have. When finished, complete the online post-test.
DOWNLOAD/PRINT CME CERTIFICATE #1
Finally, Attend the Live Hands-On Date and Complete Your Small-Group Hands-On Training in Botox and Dermal Fillers, and/or PRP with Microneedling.
RECEIVE HANDS-ON CERTIFICATE #2
📍🗓️🛒Course Location, Dates, and Registration
🗓️Saturday April 25, 2026
🗺️ PracticalCME Hands-On Training Center at PRN Medical in Santa Ana (Tustin)
Hands-On Class Times
🕐1-6pm Regenerative Aesthetics
📃SEE THE REGENERATIVE AESTHETICS COURSE OUTLINE
🖥️ REGENERATIVE AESTHETICS TRAINING COURSE VIDEO
Add on BTX/Filler Hands-On CME for a discounted rate at 8am on the same day if desired.
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4-PROCEDURE (Botox, Filler, PRP, Microneedling & Exosomes) FAST TRACK® Hands-On Certification Saturday April 25, 2026 8am, Los Angeles (Santa Ana, CA) (23 hours) 🔴SOLD OUT🔴
$5,390.00Original price was: $5,390.00.$4,890.00Current price is: $4,890.00.-
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Botulinum Toxin & Dermal Filler FAST TRACK® Hands-On Certification Saturday April 25, 2026 8am, Los Angeles (Santa Ana, CA) (11 hours) 🔴SOLD OUT🔴
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Botulinum Toxin (No Dermal Filler) FAST TRACK® Hands-On Certification Saturday April 25, 2026 8am, Los Angeles (Santa Ana, CA) (6 credits)🔴SOLD OUT🔴
$2,195.00-
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Regenerative Aesthetics™ (Microneedling, Exosomes, PRP Training) FAST TRACK® Hands-On Certification Saturday April 25, 2026 1pm Los Angeles (Santa Ana, CA) (12 hours)🟢2+ SEATS LEFT🟢
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4-PROCEDURE (Botox, Filler, PRP, Microneedling and Exosomes) FAST TRACK® Hands-On Certification Saturday May 30, 2026 8am, Los Angeles (Santa Ana, CA) (23 hours) 🟡1 SEAT LEFT🟡
$5,390.00Original price was: $5,390.00.$4,890.00Current price is: $4,890.00.-
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Botulinum Toxin (No Dermal Filler) FAST TRACK® Hands-On Certification Saturday May 30, 2026, 8am, Los Angeles (Santa Ana, CA) (6 hours) 🟡1 SEAT LEFT🟡
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Botulinum Toxin & Dermal Filler FAST TRACK® Hands-On Certification Saturday May 30, 2026 8am, Los Angeles (Santa Ana, CA) (11 hours) 🟡1 SEAT LEFT🟡
$2,795.00-
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Regenerative Aesthetics™ (Microneedling, Exosomes, PRP Training) FAST TRACK® Hands-On Certification Saturday May 30, 2026 1pm Los Angeles (Santa Ana, CA) (12 hours) 🟡1 SEAT LEFT🟡
$2,595.00-
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📃Los Angeles Regenerative Aesthetics Course Outline
🖥️ All Courses Feature Blended Online + Live FAST TRACK Training
🖊️ 🩸Microneedling and Spun PRP Hands-On
👨⚕️ One-On-One Supervised MD-Supervised Hands-On (Limit 5 per class)
🎗️ 12.75 Combined Contact Hours: 7.75 Hour AMA, AANP, ANCC accredited Streaming Online Course plus 5-Hour Live Hands-On with 2 Certificates (See Full CME Credit Statement)
Online Course Target Audience
This activity is intended for healthcare professionals involved in aesthetic medicine or seeking to incorporate regenerative aesthetic procedures into clinical practice, including physicians (MD/DO), nurse practitioners, physician assistants, and registered nurses practicing within their professional scope.
Online Course Statement of Need/Program Overview
The purpose of this activity is to provide healthcare professionals with evidence-based education on regenerative aesthetic procedures, including platelet-rich plasma (PRP) and microneedling. The activity reviews the scientific principles, clinical techniques, and safety considerations necessary to support safe and effective incorporation of these procedures into clinical practice.
Online Course Educational Objectives
After completing this activity, the participant should be better able to:
- Describe the biologic mechanisms underlying regenerative aesthetic therapies, including platelet-rich plasma, microneedling, and related biologic treatments.
- List appropriate patient selection criteria for regenerative aesthetic procedures involving PRP, microneedling, and topical biologic therapies.
- Identify clinical indications for regenerative aesthetic procedures involving PRP, microneedling, and topical biologic therapies
- Describe appropriate techniques for preparation and administration of platelet-rich plasma, including isolation, concentration, activation, and treatment protocols.
- Apply microneedling treatment parameters and protocols for facial rejuvenation and other aesthetic indications.
- Recognize potential complications and contraindications associated with regenerative aesthetic procedures.
- Implement appropriate management strategies to address complications and contraindications associated with regenerative aesthetic procedures
- Evaluate emerging regenerative therapies and adjunctive technologies within the context of evidence-based aesthetic practice.
Online Course Faculty
Gregory P. Zengo, MD
Medical Director, PracticalCME Medical Training
ONLINE COURSE AGENDA (7.75 Hours Complete at your Own Pace)
Introduction to Regenerative Aesthetics
- Principles and clinical applications of regenerative aesthetic therapies
Platelet Biology and Tissue Regeneration
- Role of platelets and growth factors in tissue repair and regeneration
Platelet-Rich Plasma (PRP): Fundamentals
- Biologic properties and clinical relevance of PRP
PRP Preparation and Processing
- Techniques for blood collection, centrifugation, and platelet isolation
PRP Activation and Treatment Protocols
- Methods of platelet activation and clinical treatment protocols
Clinical Applications of PRP
- Use of PRP in facial rejuvenation, hair restoration, and scar treatment
Microneedling: Mechanisms and Techniques
- Mechanism of action and clinical application of microneedling
Microneedling Devices and Technology
- Device selection, safety considerations, and regulatory aspects
Combination Regenerative Therapies
- Integration of PRP with microneedling and other aesthetic treatments
Emerging Biologic Therapies
- Overview of emerging biologic and adjunctive regenerative treatments
Safety, Contraindications, and Complications
- Patient selection, safety considerations, and complication management
Regulatory and Practice Considerations
- Regulatory, scope of practice, and evidence-based considerations
Summary and Clinical Integration
- Application of regenerative therapies in clinical practice
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Regenerative Aesthetics Live Hands-On Certification (5 Hours)
Synthesizing the elements of Regenerative Aesthetics in application to patient care
The hands-on faculty member will present his/her own summary of the patient selection, indications, performance, and treatment intervals of the Regenerative Aesthetic procedures she/he has used in practice. Patient consent and the basic patient evaluation will be discussed.
Q&A and Learner Assessment
Attendees will have opportunity to ask questions generated by the prerequisite online material or the information from the Online Course above.
Hands-On Assessment and Treatment
Attendees will participate in patient assessment, treatment plan, and consent of patients for the treatment. Microneedling will be performed hands-on under faculty guidance. PRP will be spun and prepared and PRP treatment will be performed under MD faculty supervision.
🖥️Regenerative Aesthetics Course Video
Los Angeles PRP Hands-On Courses for Nurses, Physicians and Nurse Practitioners are taught by PracticalCME throughout the year. PracticalCME’s FAST TRACK ™️️️ Online plus Live Blended learning allows participants to learn the material at home at your own pace prior to the live hands-on training date. You will be fully confident in your knowledge, and have already earned your first of two CME certificates before you even attend the live Los Angeles class date. There you will experience…
- All MD Faculty with at least 10 years’ experience
- Maximum of 4 Participants per live hands-on class
- One-on-One Supervised Injection of your own Patient
- Complete Post-Training Support (email contact, customizable consent forms)
- Optional same-day Hands-On Platelet-Rich Plasma Training
Our blended dual-certification online + live training is second to none in the industry. PracticalCME has earned an average of 4.8 stars in reviews from actual attendees since our first blended FAST TRACK PRP and Microneedling Training Course was held in 2014. We have paired up our Toxin and Filler Training with Cosmetic Platelet-Rich Plasma (PRP) so that you can certify in both at the same live training date, because we know your time is valuable.
Los Angeles PRP Training CME
PracticalCME Training Center, Irvine, CA
Los Angeles PRP Certification Courses
Live Los Angeles CME Certification, Platelet-Rich Plasma Certification
SINCE 2008, PRACTICALCME HAS BEEN THE LEADER IN SMALL-GROUP LIVE TRAINING COURSES AND ONLINE VIDEO COURSES IN POPULAR AESTHETIC AND WELLNESS SERVICES OFFERING CME CREDIT AND CERTIFICATION TO HUNDREDS OF DOCTORS, NURSE PRACTITIONERS, PHYSICIAN ASSISTANTS, AND NURSES.
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CME-accredited Los Angeles PRP Training Course | Frequently Asked Questions
What is a PRP Facelift?
The PRP facelift (also known as a Vampire Facelift (TM) is a combination of using hyaluronic acid dermal filler plus freshly spun platelet-rich plasma at the same treatment.
What is a PRP Facial?
The PRP facial (also known as a “Vampire Facial”) is a medical microneedling performed using freshly drawn platelet-rich plasma on the skin as the lubricant.
How do I get my PRP Certification?
One should only trust a Cosmetic PRP course that is fully approved with CME credits to ensure completeness and lack of bias. The PracticalCME course includes video clips of the procedure and live links to over 60 studies from the medical literature to support our protocols.
Who can enroll in this PRP certification course?
The PRP certification course is open to RN’s, NP’s, PA’s, MD’s, DO’s and Dentists.
What are the benefits of PRP facials?
The combination of microneedling with PRP has been shown to help skin glow, texture, fine lines, wrinkles, uniformity and, when done on a regular basis, even acne scarring.
Do Your PRP Training Courses Include Live Demonstrations?
Yes! Our live office-based platelet-rich plasma training courses include demonstrations of PRP facelifts, microneedling, or both.
If you choose our live hotel-based training course, you can enjoy a demonstration of microneedling. Office-based trainings offer both spun-blood PRP demonstration along with microneedling hands-on.
What Makes PracticalCME the Best Choice for PRP Certification?
PracticalCME has been a leader in small-group, hands-on platelet-rich plasma training since 2008. Since we want to take our trainees’ learning to the next level, we offer a complete microneedling curriculum as part of our PRP courses.
As a result, those who take our PRP training courses will learn everything they need to know about two of the most sought-after injectable cosmetic treatments through a single certification program.
In addition, our courses are taught only by MD instructors with at least 10 years of experience. We are fully committed to never canceling a class and offering plenty of resources to help you build your career as a PRP treatment provider.
Do You Offer PRP Training for Nurses?
Yes, we do! Our microneedling and PRP training is suitable for medical professionals, including registered nurses (RNs) and nurse practitioners.
Doctors, MDs and DOs, physician assistants, and other medical professionals can also take our PRP training courses.
Also, non-US licensed providers can take our online course, but our hands-on training is only open to US residents.
How Would You Describe Your PRP Certification Course?
At PracticalCME, we want to help medical professionals learn everything they need to know about PRP procedures through comprehensive training. However, our courses are not like the rest.
We offer FAST TRACK blended training on platelet-rich plasma (PRP) therapy, combining online course material with hands-on practice.
In addition, our platelet-rich plasma training courses are backed by the gold standard in CME certification.
Are All of Your PRP Injection Training Courses Online?
No, they aren’t! As mentioned, we take a blended approach for our platelet-rich plasma training, so our courses include online content (videos and links to high-quality resources) with hands-on sessions.
Are Your PRP Classes Private?
Our hands-on courses on platelet-rich plasma (PRP), also known as autologous platelet-rich plasma, are semi-private. These sessions are limited to six providers per MD instructor in order to offer personalized, one-on-one training.
What Will I Learn If I Take Your PRP Training Course?
With our blended courses, medical professionals can learn everything they should know about platelet-rich plasma procedures, wound healing, face lifting, hair regrowth, and many other benefits related to PRP therapy.
Additionally, our course material contains valuable information on cosmetic PRP facial and microneedling techniques, FDA-approved PRP isolation devices, and the growth factors present in platelets, which include the following:
- PDGF (Platelet derived growth factor)
- VEGF- (Vascular endothelial growth factor)
- PDAF-(Platelet-derived angiogenesis factor)
- EFG-(Epidermal growth factor)
- FGF-(Fibroblast growth factor)
- IGF-(Insulin Growth Factor)
- TGF-α&β (Transforming Growth alpha and beta)
- TGF-β (Transforming growth factor beta)
- TGF-β CTGF/CCN2 (Connective tissue growth factor)
What Makes Your Platelet-Rich Plasma Training Unique?
Many factors make our PRP course unique, such as the following:
- Comprehensive material on PRP facelift and facial in just one training program
- Printable online CME certificate after passing post-test and additional 7 hour CME certificate after attending live hands-on classes
- Semi-private classes
- Opportunities to perform medical microneedling and administer PRP injections during the hands-on practice
- No sponsors controlling the course’s curriculum
- Content taught by experienced MDs
- Learn at your own pace
- Downloadable customizable consents and patient instruction forms
- Free updates for two years
I Want To Provide Aesthetic Treatments But Don't Know Where To Start. Can PracticalCME Help Me?
Yes, we can! One of our main goals is to provide safe, evidence-based training before, during, and after the live hands-on practice date. In addition, our physician faculty members are willing to support students as they transition to providers of PRP treatments.
Is PRP FDA-Approved?
Platelet-Rich Plasma itself has no status with the FDA as it is a natural product, however, PRP isolation equipment must be cleared by the FDA as a Class 2 device for sale in the USA.
We discuss all FDA-cleared devices in our online course.
Here is more information from the FDA.
Is Microneedling FDA approved?
Microneedling as a procedure requires providers to use equipment that is FDA-cleared for use.
There are only a handful of pens cleared for this purpose and our online course discusses all of them.
For more information see the FDA page.