Regenerative Aesthetic Procedures Training (PRP, Microneedling, and Biologic Therapies)
Regenerative Aesthetic Procedures Training (PRP, Microneedling, and Biologic Therapies)
- Course Dates – 4/13/2026 – 4/13/2027
- This activity is jointly provided by Global Education Group (Global) and PracticalCME, LLC.
✅ On-Demand Online Course Access With Free Updates
✅ Ideal for Providers already skilled at Toxin & Fillers or Wishing to Focus on Drug-Free Aesthetic Services
✅ Print Your 7.75 Hour AMA, AANP, or ANCC Certificate at Home
✅ Order Today and Start Learning Tonight
Platelet-Rich Plasma
Since 2008, PracticalCME’s All-MD Faculty has taught Fully Accredited, Online Certification Classes including Online PRP and Microneedling Training featuring a printable CME Certificate.
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🛒 REGISTER NOW and Begin Learning Tonight
Looking for PRP training online with real CME accreditation you can use for credentialing and insurance? PracticalCME’s Regenerative Aesthetics™ online certification is a 7.75-hour, self-paced streaming course covering platelet-rich plasma (PRP) training, microneedling certification, and exosome therapies for aesthetic applications.
This is the only online PRP course with triple accreditation from AMA, AANP, and ANCC, meaning physicians, nurse practitioners, PAs, and registered nurses all earn recognized continuing education credits from a single program. Originally launched in 2014 as the world’s first CME-accredited cosmetic PRP and microneedling course, this fully redesigned 2026 edition features 60+ peer-reviewed references, downloadable protocols and consent forms, and a printable CME certificate upon completion.
Whether you are adding regenerative aesthetics to an existing practice, seeking a PRP certification for a new medspa role, or preparing for optional live hands-on training in 13 cities, this is the evidence-based online foundation trusted by hundreds of providers nationwide.

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📃COURSE OUTLINE: Regenerative Aesthetic Procedures Training (PRP, Microneedling, and Biologic Therapies)
🖥️ Streaming Online at Your Own Pace
👨⚕️ Upgradeable to add an additional Live Hands-On Training Class (Email us for Details)
🎗️ 7.75 CME Credits with 1-Year Online Course Access and Free Updates
Target Audience
This activity is intended for healthcare professionals involved in aesthetic medicine or seeking to incorporate regenerative aesthetic procedures into clinical practice, including physicians (MD/DO), nurse practitioners, physician assistants, and registered nurses practicing within their professional scope.
Statement of Need/Program Overview
The purpose of this activity is to provide healthcare professionals with evidence-based education on regenerative aesthetic procedures, including platelet-rich plasma (PRP) and microneedling. The activity reviews the scientific principles, clinical techniques, and safety considerations necessary to support safe and effective incorporation of these procedures into clinical practice.
Educational Objectives
After completing this activity, the participant should be better able to:
- Describe the biologic mechanisms underlying regenerative aesthetic therapies, including platelet-rich plasma, microneedling, and related biologic treatments.
- List appropriate patient selection criteria for regenerative aesthetic procedures involving PRP, microneedling, and topical biologic therapies.
- Identify clinical indications for regenerative aesthetic procedures involving PRP, microneedling, and topical biologic therapies
- Describe appropriate techniques for preparation and administration of platelet-rich plasma, including isolation, concentration, activation, and treatment protocols.
- Apply microneedling treatment parameters and protocols for facial rejuvenation and other aesthetic indications.
- Recognize potential complications and contraindications associated with regenerative aesthetic procedures.
- Implement appropriate management strategies to address complications and contraindications associated with regenerative aesthetic procedures
- Evaluate emerging regenerative therapies and adjunctive technologies within the context of evidence-based aesthetic practice.
Faculty
Gregory P. Zengo, MD
Medical Director, PracticalCME Medical Training
ONLINE COURSE AGENDA (Complete at your Own Pace)
Introduction to Regenerative Aesthetics
- Principles and clinical applications of regenerative aesthetic therapies
Platelet Biology and Tissue Regeneration
- Role of platelets and growth factors in tissue repair and regeneration
Platelet-Rich Plasma (PRP): Fundamentals
- Biologic properties and clinical relevance of PRP
PRP Preparation and Processing
- Techniques for blood collection, centrifugation, and platelet isolation
PRP Activation and Treatment Protocols
- Methods of platelet activation and clinical treatment protocols
Clinical Applications of PRP
- Use of PRP in facial rejuvenation, hair restoration, and scar treatment
Microneedling: Mechanisms and Techniques
- Mechanism of action and clinical application of microneedling
Microneedling Devices and Technology
- Device selection, safety considerations, and regulatory aspects
Combination Regenerative Therapies
- Integration of PRP with microneedling and other aesthetic treatments
Emerging Biologic Therapies
- Overview of emerging biologic and adjunctive regenerative treatments
Safety, Contraindications, and Complications
- Patient selection, safety considerations, and complication management
Regulatory and Practice Considerations
- Regulatory, scope of practice, and evidence-based considerations
Summary and Clinical Integration
- Application of regenerative therapies in clinical practice
✅Structured, evidence-based curriculum
✅Designed for clinicians entering aesthetic medicine
✅Covers both foundational science and clinical application
✅Prepares participants for integration into practice
🏅CME Accreditation Information
Program: 7.75-Hour Online Course
Physician Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and PracticalCME, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.
* This CME/CE activity complies with all requirements of the federal Physician Payment Sunshine Act. If a reportable event is associated with this activity, the accredited provider managing the program will provide the appropriate physician data to the Open Payments database.
Physician Credit Designation
Global Education Group designates this enduring material for a maximum of 7.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education
This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners® (AANP) through the joint providership of Global Education Group and PracticalCME, LLC. Global Education Group is accredited by AANP as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 7.75 contact hours (which includes 0.0 hours of pharmacology).
Nursing Continuing Education
Global Education Group is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.
This educational activity for 7.75 contact hours including 0.0 pharmacotherapeutic contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistant
AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 7.75 hours of Category 1 credit for completing this program.
Disclosure of Relevant Financial Relationships
Global adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
Global Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.
❔Why Choose PracticalCME over other Online Trainings?
Why Choose PracticalCME for Online PRP & Microneedling Training?
| Feature | PracticalCME Online PRP Training | Other Online PRP Courses |
|---|---|---|
| Accreditation | ✔ CME-accredited for AMA Category 1, AANP, ANCC, and AAPA credit. | ✘ Often not accredited; just a paper certificate not valid for insurance credentialing |
| Course Updates | ✔ Free updates included for 1 year. | ✘ Additional fee or no updates |
| Certificate | ✔ Print your CME certificate instantly at home | ✘ Wait for mailed copy or special request |
| Proven Track Record | ✔ First CME-accredited PRP & Microneedling course since 2014 with dozens of updates | ✘ Many newer, non-accredited providers |
| Evidence-Based Curriculum | ✔ Every protocol backed by peer-reviewed research (See Literature) | ✘ Often anecdotal with limited scientific references |
| Upgrade Options | ✔ Apply tuition toward live hands-on training | ✘ No credit toward in-person courses |
🥼Meet Your MD Faculty for Online Regenerative Aesthetics™ Training
Your faculty for the online course is
He has been a medical director of 3 different medspas and has hired and worked with numerous NP’s and RN’s in aesthetics outside of PracticalCME. His journey to aesthetics began after a successful career as Chief Resident of the nation’s second largest OB/GYN residency to become the youngest Assistant Professor at Emory University School of Medicine, and a career in private practice and academic medicine. As the lead medical director of PracticalCME since 2008, he remains in charge of CME accreditation and the online curriculum. The online course is a potent combination of the experience of our all-MD faculty blended with a rigorous review of the medical literature. In addition to authoring the world’s first CME-accredited course on PRP and Microneedling in 2014, he did the same for PDO threads in 2018. Dr. Zengo is licensed in 6 states.
❔Why Book Online PRP Training and Print Your CME Certificate?
➡️ 1. You have experience but need a CME Certificate for your liability insurance or new employer.
➡️ 2. You have a colleague who can do your hands-on supervision locally and just need basic training without the travel expense.
➡️ 3. You are not getting great results from your prior training and need to enhance your patient selection, treatment planning, and technique.
➡️ 4. You are skilled in Neurotoxins and Fillers and want to add PRP and Microneedling without hands-on since PRP uses a similar but more straightforward injection technique than the other injectables.
❓ Frequently Asked Questions About Online PRP and Microneedling Training
Is this online PRP training course CME accredited?
Yes. This is one of the only online PRP and microneedling courses with triple accreditation: AMA PRA Category 1 Credits™ (for physicians and PAs), AANP contact hours (for nurse practitioners), and ANCC contact hours (for registered nurses). The course is jointly provided by Global Education Group and PracticalCME, LLC, and is accredited through the ACCME. PracticalCME created the first-ever CME-accredited cosmetic PRP and microneedling training in 2014, and this fully redesigned 2026 edition carries the broadest accreditation of any online PRP course available today.
Who is eligible for the online PRP and microneedling certification?
The course is open to physicians (MD/DO), nurse practitioners, physician assistants, and registered nurses. Naturopathic doctors (NDs) in Washington, California, and Arizona are also eligible. Non-US licensed providers and other licensure types such as aestheticians may enroll in the online course for educational purposes. All participants should verify that PRP and microneedling procedures fall within their state or country scope of practice before incorporating them into clinical use.
What topics does the online Regenerative Aesthetics course cover?
The 7.75-hour streaming course covers platelet biology and tissue regeneration, PRP preparation and centrifugation protocols, PRP activation and clinical injection techniques, microneedling mechanisms and device selection, combination PRP and microneedling therapies, emerging biologic treatments including exosomes, patient selection and contraindications, complication management, and regulatory and scope-of-practice considerations. All protocols are supported by 60+ clickable links to peer-reviewed primary literature.
Can I take this PRP training entirely online, or do I need hands-on?
The online course can be taken as a standalone certification. Many providers choose this option when they already have injection experience, have a local supervising physician who can provide hands-on mentorship, or need a CME certificate for liability insurance or employer credentialing. If you also want direct MD-supervised hands-on training, the online course serves as the prerequisite for PracticalCME’s live Regenerative Aesthetics™ sessions, offered in 13 cities nationwide. You can upgrade to add hands-on at any time after purchasing the online course.
How long do I have access to the online PRP course, and are updates included?
You receive instant access to the streaming course the moment you register, and your access includes free updates for the duration of the course term. The course is self-paced, so you can complete it in a single sitting or spread it across multiple sessions. Upon passing the post-test, you can immediately download and print your CME certificate from home.
Who teaches the online PRP and microneedling course?
The course is taught by Gregory Zengo, MD, PracticalCME’s medical director, who authored the world’s first CME-accredited cosmetic PRP and microneedling curriculum in 2014. Dr. Zengo has over 22 years of aesthetic injection experience and is licensed in seven states. The curriculum combines clinical experience from PracticalCME’s all-MD faculty with a rigorous review of the peer-reviewed medical literature.
No training course alters the legal scope of practice as defined by the medical/nursing boards in your home state/country. Please review all state/country requirements for supervision for these procedures prior to adding them to your practice.
Reviews
I took the hands-on toxin/filler and hands-on PRP/microneedling courses on the same day. I highly recommend this cme for all physicians looking for training because it is taught by a physician (very rare) and recommends only FDA approved indications/treatment options. I appreciate his approach in discussing the clinical data and recommendations on treatments aimed at efficacy - not for the sole purpose of extracting every last cent out of a client. I know it is a business in the end but most of what others recommend take s only into account maximizing profits without regard for true efficacy. As a physician, we are trained to recommend and provide treatments that are safe and efficacious above all else. Making money is secondary when treating real human beings. Thank you Dr. Zango!
Read MoreTraining with Dr. Huyen was relaxed and enjoyable. I feel much more confident starting Tox/Fillers and Microneedling with PRP in practice now. I am glad I did both courses and look forward to more advanced courses through PracticalCME with Dr. Huyen as an incredible instructor.
Read MoreDr. Amy BairWhite Sands Medical GroupI recently completed the PRP and Microneedling training, and I found both the online and in-person portions excellent. The online course was very easy to comprehend—educational, informative, and well-structured. As a registered nurse and licensed esthetician, I’m excited to add microneedling to my practice and offer this promising service to my clients. I truly look forward to seeing the skin transformations it can bring. The in-person training was smooth and well organized. Dr. Zengo was not only clear and thorough in his explanations, but he also shared valuable moral insights about practicing responsibly in this field. He answered all of our questions with patience and demonstrated mastery of the subject matter. Overall, I feel confident and inspired after this training and would highly recommend it to others looking to expand their skills in aesthetic treatments.
Read MoreDr. Zengo
I am so thankful I found your company for my education. After taking your courses, my fear of not mastering these skills faded into excitement and confidence.
As I move forward, I will have questions. Knowing that you are willing to be a resource and answer those questions adds an additional layer of confidence that I can safely reach my goals.
Your passion and dedication to excellence is a gift you share with your students. Thank you so very much.
Read MoreP.W.Botulinum Toxin Filler Atlanta July 2025Fantastic! I completed PracticalCME training for Botulinum Toxin, Fillers, and Microneedling. From the beginning, I could not have asked for better! Dr. Zengo is extremely responsive to questions, phone calls, emails, online chats. He is so knowledgeable. The online didactic was clear and concise. There was so much covered in the lecture. I appreciated the downloadable and printable slides for note taking and reference. For the hands on training, I spent the day with Dr. Roop Monica Gill. The day was full of useful knowledge. She is a rock star! She is knowledgeable, highly skilled, approachable, and extremely personable. I feel like I have a new colleague and friend! Some of the additional information I obtained from this class was regarding legality and business tips. This information is crucial. I would highly recommend this course to anyone interested in pursuing medical aesthetics.
Read MoreSuzanne Venuti-CohenWest Palm Beach July 2025Great class! Any time you leave with more than expected it is a good feeling. The PracticalCME PRP Training class was just that from start to finish. Dr.Huyen Transform Aesthetic Center was the perfect ending. Her center was a relaxing and comfortable place to learn a new skill. She and her staff made you feel welcome. Gave informative real-life applications. Made sure we had a firm understanding of the information and could perform all steps of the procedure.
Read MoreKathleen ChristianKChristian LCC Orlando PRP Training July 2022Online didactic material was comprehensive and thoroughly addressed all aspects of treatment. Dr. Huyen provided exceptional hands on training in a professional and supportive setting. I highly recommend this course and live training.
Read MoreMolly SimpsonOrlando April 2022I really learned a lot in a matter of 6 hours. It was truly hands on and the small group size was perfect for that. Dr. Huyen was very knowledgeable and personable. I was a novice when I arrived and left feeling comfortable doing all three procedures. I highly recommend the course.
Read MoreMihaela CarterOrlando Botulinum Toxin/Filler/PRPExcellent course
Read MoreNidal RadwanPracticalCME Hands-On TrainingThis course and the hands on instruction will truly be a game changer for my new practice.
Read MoreTammy CarterHands-On Course 2021Great experience! Highly recommended.
Read MoreKarlaNovember 2020 PRP Botulinum Toxin/FillerAwesome course
Read MoreGreat hands on experience. Highly recommend.
Read MoreLynsey MaterniOrlando PRPDr. Zengo is a fabulous teacher. Great hands on. Very thorough. I feel like I have a great foundation and I’m ready to start practicing. Am going to take more courses with this group. Thank you for a great informative experience.
Read MoreKacian Brown, MDOrlando Botulinum Toxin/Filler PRPThe online learning was outstanding. And then the hands-on class surpassed my expectations. Excellent instruction aimed at getting the most hands-on experiences for each student with Botox, Fillers, & PRP. The small class was just perfect. So glad I chose Practical CME....I will definitely use them again!
Read MoreThis is a great way to get hands on training on using facial fillers, Botox and PRP. I learned about marketing , safety, patient selection and accurate patient evaluation. Overall, it's an enjoyable day packed with information. The instructors are very experienced but still remember how it feels to learn a new skill. They are patient and fun.
Read MoreVery thorough. Hands on portion was informative and we left the day feeling ready to start practicing the new skills we learned.
Read MoreGreat class, very informative.
Read MoreJulie Root, RNPRP LA 10/19Very informative, hands on was perfect! Will definitely be signing up for other classes.
Read MoreKaren O’DayEverCare Family Practice LLCYour class is very structured and informative. Thank you very much .
Read MoreEden DabalusBotulinum Toxin/Fillers PRP Los Angeles
