Botox Training Los Angeles with Dermal Filler Certification and Cosmetic PRP Training with Microneedling Hands-On in Irvine, CA

Why Take Botox and Filler Training in Los Angeles with PRP Training from PracticalCME?

Since 2008, PracticalCME has taught PREMIUM, Small-Group Hands-On Classes for Botox Injector Training in the Los Angeles (Irvine, CA) Area, and is the ONLY Botox Injection Training Provider in Los Angeles that does ALL of the following…

  • We have an All-MD Faculty.  You know the Board-Certified MD who PracticalCME offers Botox Training, Dermal Filler Certification and other aesthetic training courses taught only by MD's in small group settings. is teaching you, and the exact location of the course in Orange County before registration.  PracticalCME is the only provider that gives this full transparency.
  • We Only Teach in Small Groups. Our Live hands-on typically has 3-4 per class.
  • CME-Accredited Certification accepted by AAFP, AMA Cat.1, ANCC, AANP, AAPA. This represents the gold standard certification for RN’s, MD’s, NP’s and PA’s.  Most other trainings fail to satisfy accreditation standards. If they don’t specify their actual CME Credit Provider, then their certificate is a worthless piece of paper.
  • Add on Microneedling and PRP Certification on the same day. Nobody else gives you this flexibility.
  • Location Transparency. You know WHO teaches the course, and the street address of the class BEFORE you register.  Why can’t other trainings tell you this up front?
  • We Deliver the Entire Course Online at Time of Registration. This is the FAST TRACK™ Blended Online followed by Live Hands-On that we pioneered in 2012.  You can register today and begin learning tonight.
  • 0% Financing Available with our partner Affirm.

Thanks for reading.  Please chat or email our medical director right now, just click LIVE CHAT link at the bottom of the page.  Ask us anything!  Now try doing that with one of the other training programs 😁.

Attend the Best Botulinum Toxin Certification Training in Southern California and Practice Confidently!

Small Group Hands-on Botox Injection Training, Botox Training, Filler Training, taught by a Physician in a course with CME accreditation.

You are only taught by MD’s who have built successful full-time aesthetic practices.  Learn from a MD’s who have hired and supervised aesthetic RN’s and NP’s, not traveling social media personalities with little experience building a successful real-world practice.

Importantly, PracticalCME teaches no “Advanced” level courses.  You learn everything that works and is demand from our one comprehensive BTX/Filler or PRP/Microneedling course.  No need to waste money on “advanced” or “Level 2” courses.

In addition, NP’s cannot be trained by RN’s and MD’s cannot be trained by NP’s or RN’s in an accredited CME environment.  We have had to re-train hundreds of students who wasted their time with unaccredited training in the past. 

With PracticalCME, you get Premium, Small-Group Botox Injection Training in Los Angeles that fully certifies you to have the skills to excel, and support for 2-Years at no extra charge. All of this for about the same price as the unaccredited, non-transparent, large group, nurse-taught training programs.

See how PracticalCME compares side-by-side to other training programs.

Your instructor in Los Angeles for hands-on in Irvine, CA is Thomas Lee, MD.  He has over 8 years of experience performing Botox and Filler Injections and has trained for PracticalCME for over 3 years. 

 He has built a successful ⭐⭐⭐⭐⭐ practice from scratch and incorporates the best of all aesthetic modalities and under one roof.  He has extensive experience training RN’s and NP’s who have gone on to full, successful aesthetic careers in his own practice and throughout the country.


The instructor for your Online portion is gregory-p-zengo-medical-director-practicalcme Gregory Zengo, MD who has injected over 1.3 million units of Botox and has done Dermal Filler Injections for 22 years. A native of Rockland County, NY, he attended medical school and residency in Atlanta where he was Chief Resident and elected Resident Teacher of the Year before joining the faculty at Emory University School of Medicine. He has been a medical director of 3 different medspas and has hired and worked with numerous NP’s and RN’s in aesthetics outside of PracticalCME.  As the lead medical director of PracticalCME since 2008, he remains in charge of CME accreditation and the online curriculum in addition to live hands-on at 4 sites. Finally, Dr. Zengo also authored the world’s first CME-accredited courses on PRP and Microneedling in 2014, and PDO Threads in 2018.

Once you register, you will be encouraged to contact either of your physician faculty members with any questions you might have before, during and after your training is complete.

  • Botox CME, Dermal Filler CME, Microneedling CME, and PRP CME on the Same Date.  
  • Blended Online + Live Botox and Filler CME Certification
  • Accredited Certification AAFP accreditation certification for PracticalCME Botox and Filler Training Courses by AAFP and AMA Category 1
  • Credits accepted by AANP , AAPA, and ANCC
  • AAFP Elective credit is accepted by the American Medical Association as equivalent to AMA PRA Category 1 Credit™ toward the AMA Physician’s Recognition Award.


First, Reserve your spot in one of our blended FAST TRACK Training Courses for the Date and Location of your Choice.


Then Watch the Online training at your own pace.  Follow clickable links and interact with our faculty for any questions you have.  When finished, complete the online post-test.



AMA Category 1 Certification Credits for this Training Course

Finally, Attend the Live Hands-On Date and Complete Your Small-Group Hands-On Training in Botox and Dermal Fillers, and/or PRP with Microneedling.


📍🗓️🛒Course Location, Dates, and Registration

🗓️Saturday August 24, 2024

Seats Available

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🗓️Saturday September 28, 2024

Seats Available

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🗓️Saturday November 9, 2024

🔜 Coming Soon

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🗓️Saturday December 14, 2024

🔜 Coming Soon
🗺️ PracticalCME Training Center
Irvine, CA

Hands-On Class Times

🕗8 am-Noon Botox & Filler
🕗8 am-10am Botox

Hands-On Class Times

🕐1-6pm PRP & Microneedling
🕐1-2:30pm Microneedling

Showing 1–8 of 18 results

LIVE INJECTION 4-PROCEDURE TRAINING (BTX, Filler, Microneedling, PRP) FAST TRACK Hands-On Course Saturday August 24, 2024 8am, Los Angeles (Irvine, CA) (20.25 credits) Original price was: $4,490.00.Current price is: $3,990.00.

INJECTION 3-PROCEDURE Hands-On Certification (BTX, Filler, Microneedling) Saturday August 24, 2024 8am, Los Angeles (Irvine, CA) (14 credits) Original price was: $3,190.00.Current price is: $3,090.00.

LIVE Botulinum Toxin & Dermal Filler FAST TRACK Hands-On Course Saturday August 24, 2024 8am, Los Angeles (Irvine, CA) (10 credits)$2,495.00

LIVE Botulinum Toxin (No Dermal Filler) FAST TRACK Course with Hands-On Saturday August 24, 2024 8am, Los Angeles (Irvine, CA) (6 credits)$1,895.00

LIVE PRP Training for Aesthetics FAST TRACK Course with Microneedling Hands-On Saturday August 24, 2024 1pm Los Angeles (Irvine, CA) (10.25 credits)$2,195.00

LIVE Medical Microneedling FAST TRACK Certification Saturday August 24, 2024 1pm Los Angeles (Irvine, CA) (4 credits)$695.00

INJECTION 4-PROCEDURE Hands-On Certification (BTX, Filler, PRP, Microneedling) Saturday September 28, 2024 8am, Los Angeles (Irvine, CA) (20.25 credits) Original price was: $4,490.00.Current price is: $3,990.00.

INJECTION 3-PROCEDURE Hands-On Certification (BTX, Filler, Microneedling) Saturday September 28, 2024 8am, Los Angeles (Irvine, CA) (14 credits) Original price was: $3,190.00.Current price is: $3,090.00.

LIVE Botulinum Toxin & Dermal Filler FAST TRACK Certification with Hands-On Saturday September 28, 2024 8am, Los Angeles (Irvine, CA) (10 credits)$2,495.00

LIVE Botulinum Toxin (No Dermal Filler) FAST TRACK Certification Course Saturday September 28, 2024 8am, Los Angeles (Irvine, CA) (6 credits)$1,895.00

LIVE Cosmetic PRP and Microneedling FAST TRACK Hands-On Course Saturday September 28, 2024 1:00pm Los Angeles (Irvine, CA) (10.25 credits)$2,195.00

LIVE Medical Microneedling Training Saturday September 28, 2024 1pm Los Angeles (Irvine, CA) (4 credits)$695.00

INJECTION 3-PROCEDURE Hands-On Certification (BTX, Filler, Microneedling) Saturday TBA, 2024 8am, Los Angeles (Irvine, CA) (14 credits) Original price was: $3,190.00.Current price is: $3,090.00.

LIVE Botulinum Toxin (No Dermal Filler) FAST TRACK Certification Course Saturday TBA, 2024 8am, Los Angeles (Irvine, CA) (6 credits)$1,895.00

LIVE Botulinum Toxin & Dermal Filler FAST TRACK Hands-On Course Saturday TBA, 2024 8am, Los Angeles (Irvine, CA) (10 credits)$2,495.00

LIVE Cosmetic PRP with Microneedling FAST TRACK Hands-On Certification Saturday TBA, 2024 1pm Los Angeles (Irvine, CA) (10.25 credits)$2,195.00

LIVE Medical Microneedling FAST TRACK Certification Saturday TBA, 2024 1pm Los Angeles (Irvine, CA) (4 credits)$695.00

🖥️ All Courses Feature Blended Online + Live FAST TRACK Training
💉20u BTX-A and 1cc Hyaluronic Acid Dermal Filler Included for Hands-On
          Additional Hands-On Can Be Performed Upon Request
👨‍⚕️One-On-One MD Supervised Hands-On (Limit 4 per Class)
🎗️10 CME Credits with 2 Years’ Online Access and Free Updates

Introduction to Aging, and Wrinkles

  • Summary of facial changes with aging
  • Psychology and Social aspects of facial aging
  • Review of non-invasive facial procedures
  • Facial Skin anatomy
  • Facial Muscle anatomy and physiology

Botox Training and Dermal Filler Training Course (Online at Your Own Pace)

  • What is it Botulinum Toxin?
  • History of Use
  • FDA approved indications for use
  • Review of the 5 different FDA-Approved Toxins and their distinguishing characteristics
  • Off-Label uses
  • Reconstitution and Low Volume Reconstitution for Accuracy
  • Choosing the right syringe to use to enhance results and avoid waste
  • Patient consent
  • Contraindications
  • Virtually Painless Injection Techniques and Design.  All areas involve detailed analysis of muscle movement causing the wrinkles, NOT a protocol or injection map.
    • Central Brow
    • Forehead
    • Crow’s Feet
    • Lateral Brow Lift
    • Medial Brow Lift (“open eye” look)
  • Advanced Indications which require additional patient selection criteria (no “advanced” course needed Find out why this matters)
    • Bunny Lines
    • Upper Lip Wrinkles (Lip Flip)
    • Gummy Smile
    • DAO – Lip Corners
    • Chin Wrinkles
    • Masseters– Face Slimming
  • Touching Up
  • Complications (very rare with our approach)
  • Choosing the Right Treatment interval
  • The 3 Things You Can Do the First Visit to build a patient for life.
  • Follow-Up

Botulinum Toxin Training Hands-On Certification (Irvine, CA Training Center LIVE Date)

  • LIVE HANDS-ON INJECTION opportunity for qualified licensed attendees (RN, NP, PA, MD, DO, DDS)
    • Course Review and Q&A with our Experienced MD Faculty
    • One-On-One Supervised hands-on with our faculty of a patient you provide.  20u BTX-A and all supplies are provided in your tuition.  Additional BTX-A hands-on can be performed upon request.


Hyaluronic Acid Dermal Filler Training Course (Online at Your Own Pace)

  • Types of Hyaluronic Acid Dermal Fillers
    • Juvederm, Restylane, Belotero, Defyne, Refyne, Vollure, Volbella, Voluma
  • FDA approved Indications
  • Contraindications
  • Patient consent
  • Depth of Injection Protocols (Superficial vs. Mid vs. Deep Dermis)
  • Dental Blocks and Local Anesthetics
  • Virtually Painless Injection Techniques and Dosage Protocols
    • Nasolabial Folds
    • Marionette Lines
    • Lip  “Reinflation” vs “Augmentation”
      • Sample Volumes and Depths for great results…
      • Vermillion Border (why it is no longer the default approach),
      • Wet-Dry Line,
      • Lip Pillar
      • Above Vermillion Border for fine wrinkles
      • Philtrum enhancement
    • Mouth corners
    • Smoker’s lines
    • 3-D Volume Enhancement
  • Touching Up and Adjusting Treatments for the Next Visit
  • Using Layered Treatments Successfully
  • Areas You MUST Avoid
  • Preventing Complications and Managing Complications with Hyaluronidase in the rare event they happen.
  • Using Skinvive® on label for cheek hydration, and off-label for crepy skin and fine lines around mouth and other sites where traditional filler is too thick.

BONUS SECTIONS (BTX/Filler Online Course only)

  • First, Introduction to PRP (BTX/Filler Course only)
  • Second, Introduction to Smooth PDO Thread Volumization (BTX/Filler Course only)
  • Finally, Kybella Basic Training (BTX/Filler Course Online Content only)

Hyaluronic Acid Dermal Filler Hands-On Certification (Irvine, CA Training Center LIVE Date)

  • LIVE HANDS-ON INJECTION opportunity for qualified licensed attendees (RN, NP, PA, MD, DO, DDS)
  • Course Review and Q&A with our Experienced MD Faculty
  • One-On-One Supervised hands-on with our faculty on a patient you provide.  Up to 1cc Hyaluronic Acid Filler and all supplies are included in your tuition.  Additional HA Filler Hands-On can be performed upon request.

Practice Building Tips and Tricks

  • Introducing a new service
  • Website SEO
  • Using Daily Deal sites to attract new patients
  • Pricing and Specials

Botox®, Skinvive®, and Kybella® are registered trademarks of Allergan, Inc.

🖥️ All Courses Feature Blended Online + Live FAST TRACK Training
🖊️ Microneedling Hands-On
🩸Spun PRP Hands-On
👨‍⚕️ One-On-One Supervised MD-Supervised Hands-On (Limit 4 per class)
🎗️ 10.25 CME Credits with 2 Years’ Online Course Access and Free Updates

 ONLINE CURRICULUM (Complete at your Own Pace)

Isolating Platelet-Rich Plasma (PRP)

  • Understand the Definition of Platelet-Rich Plasma (PRP) facial procedure
  • Learn the growth factors present in platelets and their functions
  • Review the FDA-approved PRP isolation devices
    • Strengths and Weaknesses of Each
    • Differences between 1.7x and 4x or higher platelet counts
  • How and Why to “Activate” PRP
  • Benefits of PRP in the medical literature
    • Medical/Wound Healing Indications
    • Review of Literature regarding cosmetic indications
      • Face lifting and filling
      • Skin tone and uniformity
      • Hair Regrowth
      • Scars

Performing the PRP Facelift (Vampire Facelift Training)

  • Cosmetic PRP Facelift Technique and Protocols
    • Patient Assessment
    • Planning the Treatment
    • Volumes of PRP and HA Filler Calculations
    • Performing the Procedure
    • Aftercare

Performing the PRP Facial (Vampire Facial Training)

  • Cosmetic PRP Facial (PRP plus Microneedling) Technique and Protocols
    • Review of Microneedling Devices
    • FDA 2018 Jurisdiction of Microneedling Devices
    • Literature review of Microneedling
    • Microneedling protocols
    • Aftercare and Skin Products to Avoid
    • Microneedling Indications as a Standalone Procedure
  • Using PRP for other Body Areas
    • Scalp Rejuvenation Protocols
    • Hand Rejuvenation Protocols
    • Cosmetic PRP Breast Atrophy/Nipple Protocols
    • PRP Scar revision Protocols
  • BONUS:  Introduction to PRP with Smooth PDO Threads
  • Marketing Your New Service
  • \”Vampire Facelift\” and \”Vampire Facial\” branding.  Is it worth it?
  • Bundling Your Service With BTX and Dermal Fillers


Platelet-Rich Plasma Hands-On Certification (Irvine, CA Training Center LIVE Date)

  • LIVE HANDS ON:  Our MD Faculty will review the course material, and host a Q&A followed by one-on-one supervised hands-on treatments.

Participants will have the opportunity to perform Medical Microneedling, Spin and Isolate PRP and Inject PRP on a suitable patient.

AAFP accreditation certification for PracticalCME Botox and Filler Training Courses

Los Angeles Botox Hands-On Courses for Nurses, Physicians and Nurse Practitioners are taught by PracticalCME throughout the year. PracticalCME’s FAST TRACK ™️️️ Online plus Live Blended learning allows participants to learn the material at home at your own pace prior to the live hands-on training date. You will be fully confident in your knowledge, and have already earned your first of two AMA Category 1 level CME certificates before you even attend the live Los Angeles class date. There you will experience…

Our blended dual-certification online + live training is second to none in the industry. PracticalCME has earned an average of 4.8 stars in reviews from actual attendees since our first blended FAST TRACK Botox Training Course was held in 2014. We have paired up our Botox and Dermal Filler Training with Cosmetic Platelet-Rich Plasma (PRP) so that you can certify in both at the same live training date, because we know your time is valuable.

Why are PracticalCME Trainees More Successful?

Our Botox Training Course focuses on customizing the treatment plan to the patient’s own movement, and never follows a “cookbook” approach. For example, we teach a different dilution and precise muscle identification techniques so you can truly isolate the true cause of the patient’s wrinkles and effectively stop the clock on their aging process even on your first few patients, without having to see the patient back for touch-up treatments. The online course material drills these techniques home with additional treatment videos demonstrating the best technique prior to your live hands-on training class.

Our Dermal Filler Training Course curriculum focuses on using less product but at the proper depth to achieve the most natural filling of static folds and wrinkles of the face, in addition to the most natural lip reinflation techniques. You will be impressed with the results when simply using the right technique and depth at your supervised hands-on treatment session. Their folds and wrinkles will disappear before your eyes while your patient remains comfortable.

PracticalCME has heard from many RN’s who took our training and taught their supervising physicians a few things upon return to the office.

Add Cosmetic PRP Hands-On Training on the same live date

Our additional training in Cosmetic PRP (Platelet-Rich Plasma) debuted in 2014 and was the first CME approved certification course ever. Because over 60 live links to the primary literature, treatment videos and customizable consent forms, support the online FAST TRACK curriculum, the course will prepare you to offer this exciting new procedure to your patients. Then, at the live hands-on training date for PRP, you will dive deeper into indications and patient selection for the procedure and perform a variable-depth microneedling treatment on your patient with one-on-one, MD supervision.

Space is limited, So Register Today and Begin Learning Tonight

Each live date is limited to 4-6 participants before it is marked SOLD OUT. In fact, PracticalCME has only around 100 live training seats in Botox and Dermal Filler Training annually. Our award-winning, all-MD faculty take time away from their own successful practices to teach only a few times a year. This is why so many people travel to experience our small-group, in-depth blended online + live certification. If the next Los Angeles live training is sold out, scroll down and register now for the next open date. You will still receive your online content and can still begin learning and earning your first certification tonight.

Los Angeles Botox Training CME
PracticalCME Training Center, Irvine, CA
Los Angeles Botox Course, PRP Certification

Live Los Angeles CME Certification Botox Training Courses, Platelet-Rich Plasma Certification


  • Training Course Options

  • All Training Courses

  • Customer Support

  • CME-accredited Los Angeles Botox Training Course | Frequently Asked Questions

    The Botox training program provides nurses with an exciting opportunity to learn from licensed professionals with over 10 years of extensive experience.

    Only six students can sign up for each course content for hands-on Botox training. The classes will be carried out under the supervision of the best Los Angeles medical professionals with degrees in MD, DDS, NP, PA, and more.

    PracticalCME offers hands-on Botox training courses throughout the year for nurses, practitioners, and other healthcare professionals.

    The live training course with additional support materials is carried out by CME-certified medical professionals in the field of aesthetic medicine and hyaluronic acid dermal fillers.

    With limited course seats available, you’ll be among the few that gain access to premium instruction on Botox injections and other dermal filler treatments in this introductory course.

    Much more than a simple overview of Botox, participants in this complete course will learn the 

    technical aspects of medical aesthetics while also learning in-depth nerve-blocking training and surgical procedures. Nurse practitioners also have the choice to get a certification for Platelet-Rich Plasma Training from CME-accredited medical professionals on the same day.

    There is no doubt that the Los Angeles Botox Hands-on Courses by PracticalCME is an incredible one-of-a-kind opportunity for nurses looking to expand their knowledge in the field of facial aesthetics.

    This comprehensive Los Angeles program is carried out under the supervision of highly experienced CME-accredited professionals, making it possible for nurses to learn from the very best and earn legitimate Botox certification.

    There are a limited number of seats available for such intensive training programs, allowing medical practitioners to get the specialized knowledge and skills they need to excel in their field. All of the courses cost a bit over $106 a month with 0% interest rates included.when you qualify for financing through our partner Affirm.

    The courses are taught by all MD degree-holding professionals who are highly experienced in the field of aesthetic techniques. This hands-on practice will provide nurses with online and live classes on Botox treatments and facial fillers.

    Students will also get real CME accreditation by the end of the course. Limited seats are offered, catering to only four to six students for each course.

    This intimate training environment makes sure students receive 100% attention from instructors and allows them to learn from the very best in the medical field.

    Expert medical professionals with MD, RN, DDS, etc., degrees are on hand to offer the highest levels of expertise when it comes to teaching nurses about proven injection techniques. The instructors also offer personalized advice to all students registering Botulinum toxin on patients.

    To achieve maximum success and confidence, students can also take advantage of both classroom and hands-on training with live patients, where they can practice one-on-one cosmetic injectables under supervision.

    The training courses are carried out by highly experienced, CME-accredited professionals, making it the perfect way to hone your skills and stay ahead of the curve. Nurse practitioners can learn from an MD faculty with over 10 years of combined experience on average.

    However, remember the courses have limited seats, accommodating only four to six students per hands-on class.

    Post-training support is also available for all nurses throughout the training course in the form of email and live chat through a submission form. Dual certification is provided by the end of the live training programs.

    This is a question that many nurses and medical professionals struggle to answer for themselves.

    It’s true that Botox training is vital to ensure safe and effective injection techniques of the popular cosmetic injectable, yet it’s also important to consider whether such training is successful from both a patient and practitioner perspective.

    PracticalCME training sessions are supervised by experienced and accredited professionals, including MDs, RNs, and DDSs who are committed to teaching safe and successful injection techniques.

    Nurses and other medical practitioners can learn emergency medicine techniques from expert and knowledgeable professionals in a meticulous and systematic manner.

    Every training session is held in an intimate environment with hands-on practice on live patients, with videos of case studies to refer to. This level of detail and attention ensures the safest and most successful Botox therapy results.

    Registered nurses also receive extensive instruction and advice on patient histories, muscle adjustments, and facial aesthetics, as well as individualized treatment plans for live patients.

    Rather than learning from a manual, trainees get to learn from experienced professionals directly working in the field on actual patients. During the training, nurses will work with real clients to administer Botulinum toxin, which will allow each participant to have a full understanding of the product and application process.

    PracticalCME offers 100 live training programs annually, with each course catering to a maximum of only six students.

    The programs are taught under the supervision of award-winning MD professionals, who offer their limited time and expertise on Botox while away from their personal practices. As a result, the application deadline is short with limited entries permitted every year.

    Interested participants can still take up the online courses and start learning at their own pace.

    Online certification is also provided after completing the virtual training program. However, all of the hands-on training options have a specific date of application and a city where the program will be held.

    While it might be tempting to pick up a book on the subject and call yourself a ‘Botox expert,’ the best way to become an effective injector is to attend CME-accredited courses like the ones offered by PracticalCME.

    In addition to the in-classroom instruction and full-length training modules, students will also have hands-on practice with real live patients during the training course.

    Yes, cosmetic Botulinum Toxin was approved in 2002.


    Safety Information